Cheesy Meatloaf Casserole Recipe: Juicy and Gooey

Introduction

Cheesy Meatloaf Casserole is a juicy, gooey weeknight wonder that combines classic meatloaf flavor with the ease of a layered casserole and an over-the-top blanket of melted cheddar. Perfect for busy families, potlucks, or comfort-food cravings, this dish delivers all the nostalgia of meatloaf with half the shaping fuss. Presented in a white ceramic baking dish, optionally garnished with chopped parsley and ketchup drizzle, this Cheesy Meatloaf Casserole offers a golden, bubbling aesthetic that elevates any table. This recipe provides a simple oven method with pantry staples, adaptable for dietary preferences, ideal for home cooks seeking a go-to dinner that brings hearty, crowd-pleasing charm to any occasion.

Ingredients

For the Meat Layer:

  • 2 lbs ground beef (80/20 or 85/15)
  • 1 cup panko or regular breadcrumbs
  • ½ cup milk
  • 2 large eggs
  • 1 small onion, finely diced or grated
  • 2 garlic cloves, minced
  • 2 tbsp Worcestershire sauce
  • 1 tbsp ketchup
  • 2 tsp kosher salt
  • 1 tsp black pepper
  • 1 tsp Italian seasoning

For the Potato Layer:

  • 2½ lbs Yukon Gold or russet potatoes, peeled and cubed
  • 4 tbsp unsalted butter
  • ½ cup milk or cream
  • ½ cup sour cream
  • 1 tsp garlic powder
  • Salt & pepper to taste

Cheesy Topping:

  • 2½ cups shredded sharp cheddar cheese, divided
  • ½ cup ketchup (optional glaze)
  • 2 tbsp brown sugar (optional, mixed with ketchup)

Serving:

  • Optional: Fresh parsley, extra ketchup
  • Suggested Accompaniments: Green beans, dinner rolls
  • Suggested Pairings: Red wine, iced tea
  • Suggested Aesthetic: Serve in a white ceramic baking dish
  • Suggested Equipment: 9×13-inch baking dish

Step-by-Step Process

  1. Preheat Oven → Preheat oven to 375°F (190°C). Lightly grease a 9×13-inch white ceramic baking dish.
  2. Make Meat Layer → In a large bowl, soak breadcrumbs in milk for 5 minutes. Add all remaining meat ingredients and mix gently until just combined—don’t overwork. Press evenly into the bottom of the baking dish like a giant meatloaf patty.
  3. Bake Meat Base → Bake uncovered 25 minutes. It will release juices—this is normal.
  4. Cook & Mash Potatoes → While meat bakes, boil cubed potatoes in salted water 12–15 minutes until fork-tender. Drain, then mash with butter, milk, sour cream, garlic powder, salt, and pepper until creamy.
  5. Add Cheese to Potatoes → Fold 1 cup shredded cheddar into the mashed potatoes.
  6. Assemble Casserole → Remove dish from oven. Carefully drain excess fat (tilt and spoon off). Spread cheesy mashed potatoes evenly over the meat layer. Sprinkle the remaining 1½ cups of cheddar on top.
  7. Optional Sweet Glaze → Mix ketchup and brown sugar; drizzle or spread over cheese.
  8. Final Bake → Return to oven and bake 20–25 minutes until cheese is bubbly and golden. Broil 2–3 minutes at the end for extra browning (watch closely!).
  9. Rest & Serve → Let rest 10 minutes before slicing. Scoop into a white ceramic baking dish (or serve straight from it).

Tips for Better Cheesy Meatloaf Casserole

  • Drain excess fat after the first bake — keeps it from getting greasy
  • Mix meat gently — tender texture
  • Use sharp cheddar — maximum flavor and melt
  • Make ahead — assemble, cover, and refrigerate up to 24 hrs; add 10–15 min bake time.
  • Present in a white ceramic baking dish to showcase the gooey layers
  • Freeze-baked or unbaked up to 3 months
Variations and Customization
  • Bacon Cheeseburger Style → Add cooked bacon crumbles + pickles on top.
  • Italian Meatloaf Casserole → Use marinara instead of ketchup + mozzarella.
  • Turkey Version → Ground turkey + extra seasoning.
  • Low-Carb → Swap potatoes for mashed cauliflower.
  • Stuffed → Mix 1 cup cheese into the meat layer before baking.
  • Mini Casseroles → Bake in muffin tins for individual portions.
Storage and Serving Tips
  • Store covered in the fridge up to 4 days.
  • Reheat at 350°F covered with foil 20–25 min.
  • Freeze whole or in portions up to 3 months; thaw overnight before reheating.
  • Serve hot and gooey—cheese must be melted!
  • Pair with green salad or roasted veggies to cut richness.
  • Present in a white ceramic baking dish with parsley for cozy, family-style charm.
Nutritional Information

Based on 10 servings:

  • Calories: 540 kcal
  • Total Fat: 34g
  • Saturated Fat: 17g
  • Cholesterol: 165mg
  • Sodium: 920mg
  • Total Carbohydrates: 28g
  • Dietary Fiber: 2g
  • Sugars: 7g
  • Protein: 32g
  • Calcium: 30% Daily Value

Note: Values with beef and full-fat dairy (turkey or low-carb versions lower calories).

Conclusion

This Cheesy Meatloaf Casserole recipe delivers juicy meatloaf and creamy mashed potatoes under a blanket of molten cheddar in every comforting bite. It transforms two classics into one easy, crowd-pleasing bake. Its layer-and-bake method and golden presentation make it a weeknight hero. Every forkful of cheesy, savory goodness delights the whole family. It’s sure to be a cherished recipe, loved for its hearty, crowd-pleasing charm.

Cheesy Meatloaf Casserole recipe

Cheesy Meatloaf Casserole Recipe: Juicy and Gooey

Cheesy Meatloaf Casserole with a juicy, gooey taste.
Prep Time 25 minutes
Cook Time 50 minutes
Total Time 1 hour 15 minutes
Servings 10

Ingredients
  

  • 2 lbs ground beef
  • 1 cup breadcrumbs
  • 2 eggs
  • lbs potatoes
  • 4 tbsp butter
  • cups cheddar
  • ½ cup ketchup optional
  • Optional: Parsley
  • Suggested Pairings: Green beans rolls

Instructions
 

  • Mix meat layer; press into a 9×13 dish.
  • Bake 25 min at 375°F; drain fat.
  • Boil and mash potatoes with cheese.
  • Spread potatoes over meat; top with more cheese.
  • Optional ketchup glaze.
  • Bake 20–25 min until golden.
  • Rest 10 min; serve in a white ceramic dish.

Notes

  • Drain fat for the best texture.
  • Store in fridge 4 days or freeze 3 months.
  • Try bacon or an Italian variation.
  • Pair with red wine.

Sarah Williams

A Registered Dietitian, enthusiastic home cook, and food lover with a deep passion for healthy living. Interest in sharing the healthy & delicious recipes to people.

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